منابع مشابه
Cataracts and NrCAM
he intracellular parasite Toxoplasma gondii hides out in a specialized compartment surrounded by the parasitophorous vacuole membrane (PVM). The PVM associates with host cell organelles, possibly as a way of scavenging lipids from the host cell. On page 95, Sinai and Joiner describe a protein that mediates this association. The new work illuminates a poorly understood aspect of parasite biology...
متن کاملNeurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites
Neurofascin and NrCAM are two axon-associated transmembrane glycoproteins belonging to the L1 subgroup of the Ig superfamily. In this study, we have analyzed the interaction of both proteins using neurite outgrowth and binding assays. A neurofascin-Fc chimera was found to stimulate the outgrowth of tectal cells when immobilized on an inert surface but not as a soluble form using polylysine as s...
متن کاملStrabismus and Congenital Cataracts
Purpose: To study the prevalence, characteristics, indications for and results of strabismus treatment secondary to congenital cataracts. Materials and methods: This was a retrospective study of 21 cases from 29 with congenital cataracts with strabismus (unilateral in 11 and bilateral in 10 cases). In 20 patients surgery on the cataracts was performed, with an intraocular lens inserted in 15 pa...
متن کاملCataracts and avionic radiations.
Nine cases of hertzian radiation cataracts are reported among personnel working in operational aviation environments, where they were irradiated repeatedly at subliminal non-thermal field intensities. The resultant ocular pathology evolved insidiously and slowly over a period of years in a similar way to other forms of radiational injury. By the time of consultation examination, all had progres...
متن کاملConnexin Mutants and Cataracts
The lens is a multicellular, but avascular tissue that must stay transparent to allow normal transmission of light and focusing of it on the retina. Damage to lens cells and/or proteins can cause cataracts, opacities that disrupt these processes. The normal survival of the lens is facilitated by an extensive network of gap junctions formed predominantly of connexin46 and connexin50. Mutations o...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2001
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1541iti2